Mucormycosis Basics

Key points

  • Mucormycosis is a serious but rare fungal infection caused by a group of molds called mucormycetes.
  • Mucormycosis mainly affects people with weakened immune systems.
  • It most commonly affects the sinuses or the lungs.
  • It can also occur on the skin after a cut, burn, or other type of skin injury.
Women coughing with a thermometer indicating a fever

Overview

Mucormycosis, sometimes called zygomycosis, is a rare but serious fungal infection caused by a group of molds called mucormycetes. These molds are common in the environment and most people are exposed to them every day without getting sick.

Usually, only people with weakened immune systems (lower ability to fight infections) get mucormycosis.

People can get exposed to mucormycetes different ways, causing different types of infections and symptoms. Murcormycosis can be deadly and requires treatment with antifungal medications. Mucormycosis is one of the most common diseases linked to mold outbreaks in healthcare settings.

Symptoms

Mucormycosis symptoms depend on which part of the body is affected. It can affect sinuses, brain, lungs, skin, stomach and intestines, or cause symptoms throughout the body. Mucormycosis most commonly affects the sinuses or the lungs and causes symptoms like cough, nasal congestion, and fever. Symptoms of skin infections include blisters and burns.

Causes and Risk

Usually, only people with certain medical conditions or on medications that lower the body's ability to fight germs and sickness get mucormycosis. Some of these conditions include cancer, organ or stem cell transplant, and wounds or burns.

People in hospital and healthcare settings
Usually, only people with weakened immune systems get mucormycosis.

People with conditions that weaken the immune system can get mucormycosis from contact with mucormycetes. They are often found in soil and in decaying organic matter, such as leaves, compost piles, or rotten wood. Breathing in fungal spores can cause lung infections. Contact with open wounds or burns can cause skin infections.

Mucormycosis does not spread from person to person.

Healthcare facilities

Outbreaks of invasive mold infections have occurred in healthcare facilities. Mold is found in all environments and patients receiving medical care are more likely to have weakened immune systems and be at risk. Mold outbreaks have occurred through air filtration systems, water leaks, and in dampened hospital linens.

Testing and treatment

Healthcare providers test for mucormycosis by taking samples of affected tissue, fluid from the lungs, or nasal discharge. Samples are tested at a laboratory.

Antifungal medications are needed to treat mucormycosis. Sometimes surgery is needed to cut and remove infected tissues.