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Occupational Health Guidelines for Chemical Hazards

January 1981
DHHS (NIOSH) Publication Number 81-123

Occupational Health Guidelines for Chemical Hazards summarizes information on permissible exposure limits, chemical and physical properties, and health hazards. It provides recommendations for medical surveillance, respiratory protection, and personal protection and sanitation practices for specific chemicals that have Federal occupational safety and health regulations. These recommendations reflect good industrial hygiene and medical surveillance practices, and their implementation will assist development and maintenance of an effective occupational health program.

Occupational Health Guidelines for Chemical Hazards

Guidelines for Chemical Hazards
Substance CAS # *Version 
Acetaldehyde 75-07-0 1992 (rev)
Acetic acid 64-19-7 1992 (rev)
Acetic anhydride 108-24-7 1992 (rev)
Acetone 67-64-1 1988
Acetonitrile 75-05-8 1992 (rev)
2-Acetylaminofluorene 53-96-3 1988
Acetylene tetrabromide 79-27-6 1992 (rev)
Acetylsalicyclic acid 50-78-2 1988
Acrolein 107-02-8 1992 (rev)
Acrylamide 79-06-1 1992 (rev)
Acrylic acid 79-10-7 1988
Acrylonitrile 107-13-1 1988
Aldrin 309-00-2 1988
Allyl alcohol 107-18-6 1992 (rev)
Allyl chloride 107-05-1 1992 (rev)
Allyl glycidyl ether 106-92-3 1988
Allyl propyl disulfide 2179-59-1 1988
4-Aminodiphenyl 92-67-1 1988
2-Aminopyridine 504-29-0 1992 (rev)
Amitrole 61-82-5 1988
Ammonia 7664-41-7 1992 (rev)
Ammonium chloride fume 12125-02-9 1988
Ammonium sulfamate 7773-06-0 1992 (rev)
n-Amyl acetate 628-63-7 1992 (rev)
sec-Amyl acetate 626-38-0 1992 (rev)
Aniline (and homologs) 62-53-3 1992 (rev)
o-Anisidine or p-Anisidine 90-04-0 1992 (rev)
Antimony 7440-36-0 1988
ANTU 86-88-4 1992 (rev)
Arsenic (inorganic compounds, as As) 7440-38-2 1988
Arsine 7784-42-1 1988
Asbestos 1332-21-4 1988
Atrazine 1912-24-9 1988
Azinphos-methyl 86-50-0 1992 (rev)
Barium chloride (as Ba) 10361-37-2 1988
Barium sulfate 7727-43-7 1988
Benomyl 17804-35-2 1988
Benzene 71-43-2 1988
Benzidine 92-87-5 1992 (rev)
Benzoyl peroxide 94-36-0 1992 (rev)
Benzyl chloride 100-44-7 1988
Beryllium & beryllium compounds (as Be) 7440-41-7 1988
Bismuth telluride, doped with Selenium sulfide 1988
Bismuth telluride, undoped 1304-82-1 1988
Boron oxide 1303-86-2 1992 (rev)
Boron tribromide 10294-33-4 1988
Boron trifluoride 7637-07-2 1992 (rev)
Bromacil 314-40-9 1988
Bromine 7726-95-6 1992 (rev)
Bromine pentafluoride 7789-30-2 1988
Bromoform 75-25-2 1992 (rev)
1,3-Butadiene 106-99-0 1992 (rev)
n-Butane 106-97-8 1988
2-Butanone 78-93-3 1988
2-Butoxyethanol 111-76-2 1992 (rev)
n-Butyl acetate 123-86-4 1992 (rev)
sec-Butyl acetate 105-46-4 1992 (rev)
tert-Butyl acetate 540-88-5 1992 (rev)
Butyl acrylate 141-32-2 1988
n-Butyl alcohol 71-36-3 1992 (rev)
sec-Butyl alcohol 78-92-2 1992 (rev)
tert-Butyl alcohol 75-65-0 1992 (rev)
n-Butylamine 109-73-9 1992 (rev)
tert-Butyl chromate 1189-85-1 1992 (rev)
n-Butyl glycidyl ether 2426-08-6 1988
n-Butyl lactate 138-22-7 1988
n-Butyl mercaptan 109-79-5 1988
o-sec-Butylphenol 89-72-5 1988
p-tert-Butyltoluene 98-51-1 1992 (rev)
Cadmium dust (as Cd) 7440-43-9 1988
Cadmium fume (as Cd) 1306-19-0 1988
Calcium carbonate 1317-65-3 1988
Calcium cyanamide 156-62-7 1988
Calcium hydroxide 1305-62-0 1988
Calcium oxide 1305-78-8 1992 (rev)
Calcium silicate 1344-95-2 1988
Calcium sulfate 7778-18-9 1988
Camphor (synthetic) 76-22-2 1992 (rev)
Caprolactam 105-60-2 1988
Captafol 2425-06-1 1988
Captan 133-06-2 1988
Carbaryl 63-25-2 1992 (rev)
Carbofuran 1563-66-2 1988
Carbon black 1333-86-4 1988
Carbon dioxide 124-38-9 1988
Carbon disulfide 75-15-0 1988
Carbon monoxide 630-08-0 1988
Carbon tetrabromide 558-13-4 1988
Carbon tetrachloride 56-23-5 1992 (rev)
Carbonyl fluoride 353-50-4 1988
Catechol 120-80-9 1988
Cellulose 9004-34-6 1988
Cesium hydroxide 21351-79-1 1988
Chlordane 57-74-9 1988
Chlorinated camphene 8001-35-2 1988
Chlorinated diphenyl oxide 1988
Chlorine 7782-50-5 1988
Chlorine dioxide 10049-04-4 1988
Chlorine trifluoride 7790-91-2 1988
Chloroacetaldehyde 107-20-0 1988
alpha-Chloroacetophenone 532-27-4 1988
Chloroacetyl chloride 79-04-9 1988
Chlorobenzene 108-90-7 1992 (rev)
o-Chlorobenzylidene malononitrile 2698-41-1 1992 (rev)
Chlorobromomethane 74-97-5 1988
Chlorodifluoromethane 75-45-6 1988
Chlorodiphenyl (42% chlorine) 53469-21-9 1988
Chlorodiphenyl (54% chlorine) 11097-69-1 1988
Chloroform 67-66-3 1988
bis-Chloromethyl ether 542-88-1 1988
Chloromethyl methyl ether 107-30-2 1988
1-Chloro-1-nitropropane 600-25-9 1988
Chloropentafluoroethane 76-15-3 1988
Chloropicrin 76-06-2 1992 (rev)
beta-Chloroprene 126-99-8 1992 (rev)
o-Chlorostyrene 2039-87-4 1988
o-Chlorotoluene 95-49-8 1988
2-Chloro-6-trichloromethyl pyridine 1929-82-4 1988
Chlorpyrifos 2921-88-2 1988
Chromic acid and chromates 1333-82-0 1988
Chromium(III) compounds (as Cr) 1988
Chromium metal 7440-47-3 1988
Clopidol 2971-90-6 1988
Coal tar pitch volatiles 65996-93-2 1988
Cobalt metal dust and fume (as Co) 7440-48-4 1988
Cobalt carbonyl (as Co) 10210-68-1 1988
Cobalt hydrocarbonyl (as Co) 16842-03-8 1988
Copper (dusts and mists, as Cu) 7440-50-8 1988
Copper fume (as Cu) 1317-38-0 1988
Cotton dust (raw) GN22 1988
Crag® herbicide 136-78-7 1988
o-Cresol 95-48-7 1988
m-Cresol 108-39-4 1988
p-Cresol 106-44-5 1988
Crotonaldehyde 4170-30-3 1988
Crufomate 299-86-5 1988
Cumene 98-82-8 1988
Cyanogen 460-19-5 1988
Cyanogen chloride 506-77-4 1988
Cyclohexane 110-82-7 1988
Cyclohexanol 108-93-0 1988
Cyclohexanone 108-94-1 1988
Cyclohexene 110-83-8 1988
Cyclohexylamine 108-91-8 1988
Cyclonite 121-82-4 1988
Cyclopentadiene 542-92-7 1988
Cyclopentane 287-92-3 1988
2,4-D 94-75-7 1988
DDT 50-29-3 1988
Decaborane 17702-41-9 1992 (rev)
Demeton 8065-48-3 1988
Diacetone alcohol 123-42-2 1988
Diazinon 333-41-5 1988
Diazomethane 334-88-3 1988
Diborane 19287-45-7 1988
1,2-Dibromo-3-chloropropane 96-12-8 1988
2-N-Dibutylaminoethanol 102-81-8 1988
Dibutyl phosphate 107-66-4 1988
Dibutyl phthalate 84-74-2 1988
Dichloroacetylene 7572-29-4 1988
o-Dichlorobenzene 95-50-1 1988
p-Dichlorobenzene 106-46-7 1988
3,3′-Dichlorobenzidine (and its salts) 91-94-1 1988
Dichlorodifluoromethane 75-71-8 1988
1,3-Dichloro-5,5-dimethylhydantoin 118-52-5 1988
1,1-Dichloroethane 75-34-3 1988
1,2-Dichloroethylene 540-59-0 1988
Dichloroethyl ether 111-44-4 1988
Dichloromonofluoromethane 75-43-4 1988
1,1-Dichloro-1-nitroethane 594-72-9 1988
1,3-Dichloropropene 542-75-6 1988
2,2-Dichloropropionic acid 75-99-0 1988
Dichlorotetrafluoroethane 76-14-2 1988
Dichlorvos 62-73-7 1988
Dicrotophos 141-66-2 1988
Dicyclopentadiene 77-73-6 1988
Dicyclopentadienyl iron 102-54-5 1988
Dieldrin 60-57-1 1988
Diethanolamine 111-42-2 1988
Diethylamine 109-89-7 1988
2-Diethylaminoethanol 100-37-8 1988
Diethylenetriamine 111-40-0 1988
Diethyl phthalate 84-66-2 1988
Difluorodibromomethane 75-61-6 1988
Diglycidyl ether 2238-07-5 1988
Diisobutyl ketone 108-83-8 1988
Diisopropylamine 108-18-9 1988
Dimethyl acetamide 127-19-5 1988
Dimethylamine 124-40-3 1988
4-Dimethylaminoazobenzene 60-11-7 1988
N,N-Dimethylaniline 121-69-7 1988
Dimethyl-1,2-dibromo-2,2-dichlorethyl phosphate 300-76-5 1988
Dimethylformamide 68-12-2 1988
1,1-Dimethylhydrazine 57-14-7 1988
Dimethylphthalate 131-11-3 1988
Dimethyl sulfate 77-78-1 1988
Dinitolmide 148-01-6 1988
o-Dinitrobenzene 528-29-0 1988
m-Dinitrobenzene 99-65-0 1988
p-Dinitrobenzene 100-25-4 1988
Dinitro-o-cresol 534-52-1 1988
Dinitrotoluene 25321-14-6 1988
Di-sec octyl phthalate 117-81-7 1988
Dioxane 123-91-1 1988
Diphenyl 92-52-4 1988
Dipropylene glycol methyl ether 34590-94-8 1988
Dipropyl ketone 123-19-3 1988
Disulfiram 97-77-8 1988
Diuron 330-54-1 1988
Endosulfan 115-29-7 1988
Endrin 72-20-8 1988
Epichlorohydrin 106-89-8 1988
EPN 2104-64-5 1988
Ethanolamine 141-43-5 1988
Ethion 563-12-2 1988
2-Ethoxyethanol 110-80-5 1988
2-Ethoxyethyl acetate 111-15-9 1988
Ethyl acetate 141-78-6 1988
Ethyl acrylate 140-88-5 1988
Ethylamine 75-04-7 1988
Ethyl benzene 100-41-4 1988
Ethyl bromide 74-96-4 1988
Ethyl butyl ketone 106-35-4 1988
Ethyl chloride 75-00-3 1988
Ethylene chlorohydrin 107-07-3 1988
Ethylenediamine 107-15-3 1988
Ethylene dibromide 106-93-4 1988
Ethylene dichloride 107-06-2 1988
Ethylene glycol 107-21-1 1988
Ethylene glycol dinitrate 628-96-6 1988
Ethyleneimine 151-56-4 1988
Ethylene oxide 75-21-8 1988
Ethyl ether 60-29-7 1988
Ethyl formate 109-94-4 1988
Ethylidene norbornene 16219-75-3 1988
Ethyl mercaptan 75-08-1 1988
N-Ethylmorpholine 100-74-3 1988
Ethyl silicate 78-10-4 1988
Ferbam 14484-64-1 1988
Ferrovanadium dust 12604-58-9 1988
Fluorine 7782-41-4 1988
Fluorotrichloromethane 75-69-4 1988
Formaldehyde 50-00-0 1988
Formic acid 64-18-6 1988
Furfural 98-01-1 1988
Furfuryl alcohol 98-00-0 1988
Glycidol 556-52-5 1988
Graphite (natural) 7782-42-5 1988
Hafnium 7440-58-6 1988
Heptachlor 76-44-8 1988
n-Heptane 142-82-5 1988
Hexachloroethane 67-72-1 1988
Hexachloronaphthalene 1335-87-1 > 1988
n-Hexane 110-54-3 1988
2-Hexanone 591-78-6 1988
Hexone 108-10-1 1988
sec-Hexyl acetate 108-84-9 1988
Hydrazine 302-01-2 1988
Hydrogen bromide 10035-10-6 1988
Hydrogen chloride 7647-01-0 1988
Hydrogen cyanide 74-90-8 1988
Hydrogen fluoride (as F) 7664-39-3 1988
Hydrogen peroxide 7722-84-1 1988
Hydrogen selenide 7783-07-5 1988
Hydrogen sulfide 7783-06-4 1988
Hydroquinone 123-31-9 1988
Iodine 7553-56-2 1988
Iron oxide dust and fume (as Fe) 1309-37-1 1988
Isoamyl acetate 123-92-2 1988
Isoamyl alcohol (primary) 123-51-3 1988
Isoamyl alcohol (secondary) 6032-29-7 1988
Isobutyl acetate 110-19-0 1988
Isobutyl alcohol 78-83-1 1988
Isophorone 78-59-1 1988
Isopropyl acetate 108-21-4 1988
Isopropyl alcohol 67-63-0 1988
Isopropylamine 75-31-0 1988
Isopropyl ether 108-20-3 1988
Isopropyl glycidyl ether 4016-14-2 1988
Ketene 463-51-4 1988
Lead 7439-92-1 1988
Lindane 58-89-9 1988
Lithium hydride 7580-67-8 1988
L.P.G. 68476-85-7 1988
Magnesium oxide fume 1309-48-4 1988
Malathion 121-75-5 1988
Maleic anhydride 108-31-6 1988
Manganese compounds and fume (as Mn) 7439-96-5 1988
Mercury compounds [except (organo) alkyl 7439-97-6 1988
Mercury (organo) alkyl compounds (as Hg) 1988
Mesityl oxide 141-79-7 1988
Methoxychlor 72-43-5 1988
Methyl acetate 79-20-9 1988
Methyl acetylene 74-99-7 1988
Methyl acetylene-propadiene mixture 59355-75-8 1988
Methyl acrylate 96-33-3 1988
Methylal 109-87-5 1988
Methyl alcohol 67-56-1 1988
Methylamine 74-89-5 1988
Methyl bromide 74-83-9 1988
Methyl Cellosolve® 109-86-4 1988
Methyl Cellosolve® acetate 110-49-6 1988
Methyl chloride 74-87-3 1988
Methyl chloroform 71-55-6 1988
Methylcyclohexane 108-87-2 1988
Methylcyclohexanol 25639-42-3 1988
o-Methylcyclohexanone 583-60-8 1988
Methylene bisphenyl isocyanate 101-68-8 1988
Methylene chloride 75-09-2 1988
Methyl formate 107-31-3 1988
5-Methyl-3-heptanone 541-85-5 1988
Methyl hydrazine 60-34-4 1988
Methyl iodide 74-88-4 1988
Methyl isobutyl carbinol 108-11-2 1988
Methyl isocyanate 624-83-9 1988
Methyl mercaptan 74-93-1 1988
Methyl methacrylate 80-62-6 1988
alpha-Methyl styrene 98-83-9 1988
Mica (containing less than 1% quartz) 12001-26-2 1988
Molybdenum 7439-98-7 1988
Molybdenum (soluble compounds, as Mo) 1988
Monomethyl aniline 100-61-8 1988
Morpholine 110-91-8 1988
Naphtha (coal tar) 8030-30-6 1988
Naphthalene 91-20-3 1988
alpha-Naphthylamine 134-32-7 1988
beta-Naphthylamine 91-59-8 1988
Nickel carbonyl 13463-39-3 1988
Nickel metal and other compounds (as Ni) 7440-02-0 1988
Nicotine 54-11-5 1988
Nitric acid 7697-37-2 1988
Nitric oxide 10102-43-9 1988
p-Nitroaniline 100-01-6 1988
Nitrobenzene 98-95-3 1988
4-Nitrobiphenyl 92-93-3 1988
p-Nitrochlorobenzene 100-00-5 1988
Nitroethane 79-24-3 1988
Nitrogen dioxide 10102-44-0 1988
Nitrogen trifluoride 7783-54-2 1988
Nitroglycerine 55-63-0 1988
Nitromethane 75-52-5 1988
1-Nitropropane 108-03-2 1988
2-Nitropropane 79-46-9 1988
N-Nitrosodimethylamine 62-75-9 1988
o-Nitrotoluene 88-72-2 1988
m-Nitrotoluene 99-08-1 1988
p-Nitrotoluene 99-99-0 1988
Octachloronaphthalene 2234-13-1 1988
Octane 111-65-9 1988
Oil mist (mineral) 8012-95-1 1988
Osmium tetroxide 20816-12-0 1988
Oxalic acid 144-62-7 1988
Oxygen difluoride 7783-41-7 1988
Ozone 10028-15-6 1988
Paraquat (Paraquat dichloride) 1910-42-5 1988
Parathion 56-38-2 1988
Pentaborane 19624-22-7 1988
Pentachloronaphthalene 1321-64-8 1988
Pentachlorophenol 87-86-5 1988
n-Pentane 109-66-0 1988
2-Pentanone 107-87-9 1988
Perchloromethyl mercaptan 594-42-3 1988
Perchloryl fluoride 7616-94-6 1988
Petroleum distillates (naphtha) 8002-05-9 1988
Phenol 108-95-2 1988
p-Phenylene diamine 106-50-3 1988
Phenyl ether (vapor) 101-84-8 1988
Phenyl ether-biphenyl mixture (vapor) 8004-13-5 1988
Phenyl glycidyl ether 122-60-1 1988
Phenylhydrazine 100-63-0 1988
Phosdrin 7786-34-7 1988
Phosgene 75-44-5 1988
Phosphine 7803-51-2 1988
Phosphoric acid 7664-38-2 1988
Phosphorus (yellow) 7723-14-0 1988
Phosphorus pentachloride 10026-13-8 1988
Phosphorus pentasulfide 1314-80-3 1988
Phosphorus trichloride 7719-12-2 1988
Phthalic anhydride 85-44-9 1988
Picric acid 88-89-1 1988
Platinum (soluble salts, as Pt) 1988
Portland cement 65997-15-1 1992 (rev)
Propane 74-98-6 1988
beta-Propiolactone 57-57-8 1988
n-Propyl acetate 109-60-4 1988
n-Propyl alcohol 71-23-8 1988
Propylene dichloride 78-87-5 1988
Propylene imine 75-55-8 1988
Propylene oxide 75-56-9 1988
n-Propyl nitrate 627-13-4 1988
Pyrethrum 8003-34-7 1988
Pyridine 110-86-1 1988
Quinone 106-51-4 1988
Rhodium (metal fume and insoluble compou 7440-16-6 1988
Rhodium (soluble compounds, as Rh) 1988
Ronnel 299-84-3 1988
Rotenone 83-79-4 1988
Selenium 7782-49-2 1988
Selenium hexafluoride 7783-79-1 1988
Silica, amorphous 7631-86-9 1988
Silica, crystalline (as respirable dust) 14808-60-7 1988
Silver (metal dust and soluble compounds 7440-22-4 1988
Soapstone (containing less than 1% quart VV87 1988
Sodium fluoroacetate 62-74-8 1988
Sodium hydroxide 1310-73-2 1988
Stibine 7803-52-3 1988
Stoddard solvent 8052-41-3 1988
Strychnine 57-24-9 1988
Styrene 100-42-5 1988
Sulfur dioxide 7446-09-5 1988
Sulfuric acid 7664-93-9 1988
Sulfur monochloride 10025-67-9 1988
Sulfur pentafluoride 5714-22-7 1988
Sulfuryl fluoride 2699-79-8 1988
2,4,5-T 93-76-5 1988
Talc (containing no asbestos and less th 14807-96-6 1988
Tantalum (metal and oxide dust, as Ta) 7440-25-7 1988
TEDP 3689-24-5 1988
Tellurium 13494-80-9 1988
Tellurium hexafluoride 7783-80-4 1988
TEPP 107-49-3 1988
o-Terphenyl 84-15-1 1988
m-Terphenyl 92-06-8 1988
p-Terphenyl 92-94-4 1988
1,1,1,2-Tetrachloro-2,2-difluoroeth 76-11-9 1988
1,1,2,2-Tetrachloro-1,2-difluoroethane 76-12-0 1988
1,1,2,2-Tetrachloroethane 79-34-5 1988
Tetrachloroethylene 127-18-4 1988
Tetrachloronaphthalene 1335-88-2 1988
Tetraethyl lead (as Pb) 78-00-2 1988
Tetrahydrofuran 109-99-9 1988
Tetramethyl lead (as Pb) 75-74-1 1988
Tetramethyl succinonitrile 3333-52-6 1988
Tetranitromethane 509-14-8 1988
Tetryl 479-45-8 1988
Thallium (soluble compounds, as Tl) 1988
Thiram 137-26-8 1988
Tin 7440-31-5 1988
Tin (organic compounds, as Sn) 1988
Titanium dioxide 13463-67-7 1988
Toluene 108-88-3 1988
Toluene-2,4-diisocyanate 584-84-9 1988
o-Toluidine 95-53-4 1988
Tributyl phosphate 126-73-8 1988
1,1,2-Trichloroethane 79-00-5 1988
Trichloroethylene 79-01-6 1988
Trichloronaphthalene 1321-65-9 1988
1,2,3-Trichloropropane 96-18-4 1988
1,1,2-Trichloro-1,2,2-trifluoroethane 76-13-1 1988
Trifluorobromomethane 75-63-8 1988
2,4,6-Trinitrotoluene 118-96-7 1988
Triorthocresyl phosphate 78-30-8 1988
Triphenyl phosphate 115-86-6 1988
Turpentine 8006-64-2 1988
Uranium (insoluble compounds, as U) 7440-61-1 1988
Uranium (soluble compounds, as U) 1988
Vanadium dust 1314-62-1 1988
Vanadium fume 1314-62-1 1988
Vinyl chloride 75-01-4 1988
Vinyl toluene 25013-15-4 1988
Warfarin 81-81-2 1988
o-Xylene 95-47-6 1988
Xylidine 1300-73-8 1988
Yttrium 7440-65-5 1988
Zinc chloride fume 7646-85-7 1988
Zinc oxide 1314-13-2 1988
Zirconium compounds (as Zr) 7440-67-7 1988

*To obtain a copy of a previous version of this communication product please contact CDC Info 1-800-CDC-INFO (1-800-232-4636)|TTY: 1-888-232-6348 l cdc.gov/info.