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| Thursday, October 23, 2008 |
Volume
21 Number 17 |
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| This weekly update provides information about the impact of human genomic research on disease prevention & population health. |
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Genetic Prevalence Estimates of the U.S. Population Published
CDC reports the first estimates of gene variant frequency for a nationally-representative sample of the U.S. population, including major racial and ethnic subgroups. This work may help us to understand how these gene variants influence health and disease outcomes.
Read more.
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- The following are headlines from on-line news articles published during the past week.
- The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
- Free registration required for some articles.
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Cancer |
Link between gene variations and cancer survival revealed by U of MN study,
Medical News Today, October 23 |
Local surgeon takes a personal look at breast cancer,
The Greenville Sun, October 21 |
Study finds BRAF mutations in colorectal cancer cause resistance to anti-EGFR therapy,
EurekAlert, October 23 |
Lung cancer genetics mapped,
eCancer News, October 21 |
Large-scale genetic study sheds new light on lung cancer, opens door to individualized treatment strategies,
NIH News, October 22 |
Discovery of a gene critical for development of lymphatic system, implications for cancer...,
Medical News Today, October 20 |
Mechanical pressure accelerates early stages of colon cancer,
Science Daily, October 22 |
Inconclusive genetic testing results might lead to anxiety about ...,
Medical News Today, October 20 |
Researchers identify pattern of gene expression that can predict how patients with advanced... ,
Medical News Today, October 22 |
Promising gene target for neuroblastoma therapy identified,
Science Daily, October 20 |
Breast cancer disparities growing among Black women in St. Louis,
The St. Louis American, October 21 |
New risk factors for basal cell carcinoma,
HUM-MOLGEN, October 16 |






Other News |
Genetics could be key to understanding autoimmune diseases, says professor,
Irish Times, October 21 |
Genetic based human diseases are an ancient evolutionary legacy,
Medical News Today, October 19 |
Rotting fish woman diagnosed with genetic condition,
Telegraph.co.uk, October 21 |
Molecule stops DNA replication in its tracks,
News-Medical.Net, October 19 |
Illumina launches GenomeStudio(TM) data analysis software,
chron.com, October 20 |
Researchers identify Achilles heel of common childhood tumor,
EurekAlert, October 19 |
UH receives grant for genomic device study,
Houston Business Journal, October 20 |
Significant number of exons created from junk DNA seem to play a role in gene regulation,
Medical News, October 19 |
Gene hunt in dyslexia,
Science Daily, October 19 |
Researchers establish International Human Microbiome Consortium,
NIH News, October 16 |
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Does the relationship between IgE and the CD14 gene depend on ethnicity?
Zhang G, et al.
Allergy 2008 Nov;63(11):1411-7
Pharmacogenetics of the neurodevelopmental impact of anticancer chemotherapy
Robaey P, et al.
Dev Disabil Res Rev 2008 Oct;14(3):211-20
Copy-number variations associated with neuropsychiatric conditions
Cook EH Jr & Scherer SW
Nature 2008 Oct;455(7215):919-23
Does COMT val(158)met Affect Behavioral Phenotypes: Yes, No, Maybe?
Lachman HM
Neuropsychopharmacology 2008 Oct
Hypertension-Associated Kidney Disease: Perhaps no More
Freedman BI & Sedor JR
J Am Soc Nephrol 2008 Oct
Strategy for a genetic assessment of antipsychotic and antidepressant-related proarrhythmia
Drago A, et al.
Curr Med Chem 2008;15(24):2472-517
Mitochondria, mitochondrial DNA and Alzheimer's disease. What comes first?
Mancuso M, et al.
Curr Alzheimer Res 2008 Oct;5(5):457-68
Human genetic factors and respiratory syncytial virus disease severity
Miyairi I & DeVincenzo JP
Clin Microbiol Rev 2008 Oct;21(4):686-703
A new model defines the minimal set of polymorphism in HLA-DQ and -DR that determines susceptibility and resistance to autoimmune diabetes
Parry CS & Brooks BR
Biol Direct 2008 Oct;3(1):42
Clinical pharmacogenetics and potential application in personalized medicine
Zhou SF, et al.
Curr Drug Metab 2008 Oct;9(8):738-84
Searching for genetic factors underlying pre-eclampsia: recent progress and persistent challenges
Ward K
Minerva Ginecol 2008 Oct;60(5):399-419
The Medical and Economic Roles of Pipeline Pharmacogenetics: Alzheimer's Disease as a Model of Efficacy and HLA-B(*)5701 as a Model of Safety
Roses AD
Neuropsychopharmacology 2008 Oct
The genetic contribution to systemic lupus erythematosus
Criswell LA
Bull NYU Hosp Jt Dis 2008;66(3):176-83
Assessing Genuine Parents-Offspring Trios for Genetic Association Studies
Teo YY, et al.
Hum Hered 2008 Oct;67(1):26-37
Carbamazepine, HLA-B*1502 and risk of Stevens-Johnson syndrome and toxic epidermal necrolysis: US FDA recommendations
Ferrell PB Jr & McLeod HL
Pharmacogenomics 2008 Oct;9(10):1543-6
Genetic variants associated with cisplatin-induced ototoxicity
Oldenburg J, et al.
Pharmacogenomics 2008 Oct;9(10):1521-30
Genetic susceptibility to eating disorders: associated polymorphisms and pharmacogenetic suggestions
Monteleone P & Maj M
Pharmacogenomics 2008 Oct;9(10):1487-520
Pharmacogenetics of apolipoprotein E gene during lipid-lowering therapy: lipid levels and prevention of coronary heart disease
Nieminen T, et al.
Pharmacogenomics 2008 Oct;9(10):1475-86
The blood pressure variability, arterial elasticity and humoral factors in subjects with family history of hypertension
Rafidah HM, et al.
Med J Malaysia 2008 Mar;63(1):9-16
The emotional impact of genetic testing and aspects of counseling prior to prescription of oral contraceptives
Gartner V, et al.
Contraception 2008 Nov;78(5):392-8
The American Cancer Society guidelines for breast screening with magnetic resonance imaging: an argument for genetic testing
Murphy CD, et al.
Cancer 2008 Oct
Memorable messages about genes and health: implications for direct-to-consumer marketing of genetic tests and therapies
Parrott R, et al.
Health Mark Q 2008;25(1-2):8-32
The brave new era of human genetic testing
Bandelt HJ, et al.
Bioessays 2008 Oct;30(11-12):1246-51
Ethnicity of children with homozygous c.985A>G medium-chain acyl-CoA dehydrogenase deficiency: findings from screening approximately 1.1 million newborn infants
Khalid JM, et al.
J Med Screen 2008;15(3):112-7
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Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the
HuGENet™ home page
For more information on HuGE, please visit the
HuGENet™ home page
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