Centers for Disease Control and Prevention Centers for Disease Control and Prevention CDC Home Search CDC CDC Health Topics A-Z topbar background lines
Office of Public Health Genomics
Centers for Disease Control and Prevention
Office of Genomics and Disease Prevention
 
 
 Thursday, October 23, 2008 Volume 21   Number 17
banner update Family History Population Research Genomics in Practice General Public
This weekly update provides information about the impact of human genomic research on disease prevention & population health. open mailbox for email deliveryGet email updates
Spotlight
image of the United States

Genetic Prevalence Estimates of the U.S. Population Published
CDC reports the first estimates of gene variant frequency for a nationally-representative sample of the U.S. population, including major racial and ethnic subgroups. This work may help us to understand how these gene variants influence health and disease outcomes. Read more.

Sections

 >  View Current Update
blue dotAnnouncements
blue dotGenomics In The News
blue dotScientific Literature
blue dotHuGE Articles
blue dotBack Issues

 Upcoming Events
Genomics Announcements
 

CDC logo
New genetics fellowship position with CDC’s Division of Laboratory Systems in the National Center for Preparedness, Detection, and Control of Infectious Disease.
   
bullhorn

New scientific journal Circulation: Cardiovascular Genetics non-gov warning icon releases first issue.

   
bullhorn

The Oregon State Genetics Program releases 2007 results on BRFSS questions pdf icon (146 KB) related to family history of cardiovascular disease and direct-to-consumer marketing of genetic tests.

   
bullhorn

Join the APHA Genomics Forum non-gov warning icon and attend the next meeting on October 26th at the annual conference of the American Public Health Association in San Diego, California.

   
bullhorn
October is National Breast Cancer Awareness Month. See the USPSTF recommendations on BRCA mutation testing for breast and ovarian cancer susceptibility, and learn more about breast cancer from the CDC and NIH.


Genomics In The News

  • The following are headlines from on-line news articles published during the past week.
  • The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
  • Free registration required for some articles.

Asthma

Identification of genetic variants predisposing to early-onset asthma and interacting with environmental exposure to tobacco-smoke in early life, non-gov warning icon Medical News Today, October 17

line

Cancer

Link between gene variations and cancer survival revealed by U of MN study, non-gov warning icon Medical News Today, October 23

Local surgeon takes a personal look at breast cancer, non-gov warning icon The Greenville Sun, October 21

Study finds BRAF mutations in colorectal cancer cause resistance to anti-EGFR therapy, non-gov warning icon EurekAlert, October 23

Lung cancer genetics mapped, non-gov warning icon eCancer News, October 21

Large-scale genetic study sheds new light on lung cancer, opens door to individualized treatment strategies, non-gov warning icon NIH News, October 22

Discovery of a gene critical for development of lymphatic system, implications for cancer..., non-gov warning icon Medical News Today, October 20

Mechanical pressure accelerates early stages of colon cancer, non-gov warning icon Science Daily, October 22

Inconclusive genetic testing results might lead to anxiety about ..., non-gov warning icon Medical News Today, October 20

Researchers identify pattern of gene expression that can predict how patients with advanced... , non-gov warning icon Medical News Today, October 22

Promising gene target for neuroblastoma therapy identified, non-gov warning icon Science Daily, October 20

Breast cancer disparities growing among Black women in St. Louis, non-gov warning icon The St. Louis American, October 21

New risk factors for basal cell carcinoma, non-gov warning icon HUM-MOLGEN, October 16

line

ELSI (Ethical, Legal and Social Issues)

Adapting to life with the risk or reality of genetic disease: genetic counselors suggest ways to help patients cope, Yahoo News, October 23

A valuable guide to ethical issues in governing biobanks: Examine the conditions under which genetic databases can be established & used ethically, non-gov warning icon Centre Daily Times, October 22

line

Genetic Testing

Missing the mark, non-gov warning icon China Daily, October 22

Taking a peek at the experts’ genetic secrets, non-gov warning icon The New York Times, October 19

Willingness to pay for genetic testing concerning depression, non-gov warning icon Medical News Today, October 22

 

line

Mental Health

New candidate genes for schizophrenia identified, non-gov warning icon EurekAlert, October 20

line

Obesity

Obese people's brains show less pleasure from eating, non-gov warning icon Medical News Today, October 17

Scientists from Granada find a potential treatment to prevent diabetes and obesity, non-gov warning icon EurekAlert, October 17

line

Personalized Medicine

Fast-changing field of medical genetics embraces personalized medicine, non-gov warning icon UCSF Today, October 21

Personal genomes posted online for research purposes, non-gov warning icon Red Orbit, October 21

line

Other News

Genetics could be key to understanding autoimmune diseases, says professor, non-gov warning icon Irish Times, October 21

Genetic based human diseases are an ancient evolutionary legacy, non-gov warning icon Medical News Today, October 19

Rotting fish woman diagnosed with genetic condition, non-gov warning icon Telegraph.co.uk, October 21

Molecule stops DNA replication in its tracks, non-gov warning icon News-Medical.Net, October 19

Illumina launches GenomeStudio(TM) data analysis software, non-gov warning icon chron.com, October 20

Researchers identify Achilles heel of common childhood tumor, non-gov warning icon EurekAlert, October 19

UH receives grant for genomic device study, non-gov warning icon Houston Business Journal, October 20

Significant number of exons created from junk DNA seem to play a role in gene regulation, non-gov warning icon Medical News, October 19

Gene hunt in dyslexia, non-gov warning icon Science Daily, October 19

Researchers establish International Human Microbiome Consortium, non-gov warning icon NIH News, October 16

line
Genomics in Scientific Literature
Featured Item

Prevalence in the United States of Selected Candidate Gene Variants: Third National Health and Nutrition Examination Survey, 1991-1994
Chang MH, et al.
Am J Epidemiol 2008 Oct


 General Articles

Does the relationship between IgE and the CD14 gene depend on ethnicity?
Zhang G, et al.
Allergy 2008 Nov;63(11):1411-7

Pharmacogenetics of the neurodevelopmental impact of anticancer chemotherapy
Robaey P, et al.
Dev Disabil Res Rev 2008 Oct;14(3):211-20

Copy-number variations associated with neuropsychiatric conditions
Cook EH Jr & Scherer SW
Nature 2008 Oct;455(7215):919-23

Does COMT val(158)met Affect Behavioral Phenotypes: Yes, No, Maybe?
Lachman HM
Neuropsychopharmacology 2008 Oct

Hypertension-Associated Kidney Disease: Perhaps no More
Freedman BI & Sedor JR
J Am Soc Nephrol 2008 Oct

Strategy for a genetic assessment of antipsychotic and antidepressant-related proarrhythmia
Drago A, et al.
Curr Med Chem 2008;15(24):2472-517

Mitochondria, mitochondrial DNA and Alzheimer's disease. What comes first?
Mancuso M, et al.
Curr Alzheimer Res 2008 Oct;5(5):457-68

Human genetic factors and respiratory syncytial virus disease severity
Miyairi I & DeVincenzo JP
Clin Microbiol Rev 2008 Oct;21(4):686-703

A new model defines the minimal set of polymorphism in HLA-DQ and -DR that determines susceptibility and resistance to autoimmune diabetes
Parry CS & Brooks BR
Biol Direct 2008 Oct;3(1):42

Clinical pharmacogenetics and potential application in personalized medicine
Zhou SF, et al.
Curr Drug Metab 2008 Oct;9(8):738-84

Searching for genetic factors underlying pre-eclampsia: recent progress and persistent challenges
Ward K
Minerva Ginecol 2008 Oct;60(5):399-419

The Medical and Economic Roles of Pipeline Pharmacogenetics: Alzheimer's Disease  as a Model of Efficacy and HLA-B(*)5701 as a Model of Safety
Roses AD
Neuropsychopharmacology 2008 Oct

The genetic contribution to systemic lupus erythematosus
Criswell LA
Bull NYU Hosp Jt Dis 2008;66(3):176-83

Assessing Genuine Parents-Offspring Trios for Genetic Association Studies
Teo YY, et al.
Hum Hered 2008 Oct;67(1):26-37

Carbamazepine, HLA-B*1502 and risk of Stevens-Johnson syndrome and toxic epidermal necrolysis: US FDA recommendations
Ferrell PB Jr & McLeod HL
Pharmacogenomics 2008 Oct;9(10):1543-6

Genetic variants associated with cisplatin-induced ototoxicity
Oldenburg J, et al.
Pharmacogenomics 2008 Oct;9(10):1521-30

Genetic susceptibility to eating disorders: associated polymorphisms and pharmacogenetic suggestions
Monteleone P & Maj M
Pharmacogenomics 2008 Oct;9(10):1487-520

Pharmacogenetics of apolipoprotein E gene during lipid-lowering therapy: lipid levels and prevention of coronary heart disease
Nieminen T, et al.
Pharmacogenomics 2008 Oct;9(10):1475-86


 Family History

The blood pressure variability, arterial elasticity and humoral factors in subjects with family history of hypertension
Rafidah HM, et al.
Med J Malaysia 2008 Mar;63(1):9-16

 

 Genetic Testing

The emotional impact of genetic testing and aspects of counseling prior to prescription of oral contraceptives
Gartner V, et al.
Contraception 2008 Nov;78(5):392-8

The American Cancer Society guidelines for breast screening with magnetic resonance imaging: an argument for genetic testing
Murphy CD, et al.
Cancer 2008 Oct

Memorable messages about genes and health: implications for direct-to-consumer marketing of genetic tests and therapies
Parrott R, et al.
Health Mark Q 2008;25(1-2):8-32

The brave new era of human genetic testing
Bandelt HJ, et al.
Bioessays 2008 Oct;30(11-12):1246-51

Ethnicity of children with homozygous c.985A>G medium-chain acyl-CoA dehydrogenase deficiency: findings from screening approximately 1.1 million newborn infants
Khalid JM, et al.
J Med Screen 2008;15(3):112-7

line
HuGE Published Literature [ back to top ]

Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page

For more information on HuGE, please visit the HuGENet™ home page

Send web sites that you would like to see included in a future update to cdcinfo@cdc.gov

To receive notification of this update by e-mail, please send the following message:
To: listserv@listserv.cdc.gov
Subject: (leave blank)
Message: subscribe genetics
(to unsubscribe, replace Message text with "unsubscribe genetics")

The CDC National Office of Public Health Genomics makes available the above information as a public service only. Providing this information does not constitute endorsement by the CDC.  Note that some links may become invalid over time.

 
This reference links to a non-governmental website
 Provides link to non-governmental sites and does not necessarily represent the views of the Centers  for Disease Control and Prevention.

Page last reviewed: October 23, 2008 (archived document)
Page last updated: August 19, 2009
Content source: National Center for Chronic Disease Prevention and Health Promotion, Public Health Genomics